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KMID : 0385019910070020107
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Korean Journal of Laboratory Animal Science
1991 Volume.7 No. 2 p.107 ~ p.111
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Genetic Monitoring of Biochemical Markers for the Genetic Assurance in Laboratory Animal Strain Maintenance
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김원용/Kim, Won Yong
김용준/최재윤/김환묵/오구택/현병화/Kim, Yong Joon/Choi, Jae Yoon/Kim, Hwan Mook/Oh, Goo Taeg/Hyun, Byung Hwa
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Abstract
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For the genetic quality assurance in laboratory animal strain maintenance, biochemical monitoring was performed. Mouse(8 strains) and rat(4 strains) were examined by using 17 and 23 biochemical markers, respectively.
In analysis of markers, electrophoresis techniques were applied using cellulose acetate membrane or polyacrylamide gel and the genetic profiles were preformed. Also, it might be assumed that the inter-strain inspection could be performed easily by analysis of critical subset of mouse, Es-2, 3, 4, Fh-1, SVP-1 of F344, LEW rat strains and Akp-1, Es-2, 4, 8, Gdc-1, Mup-1, Pgd of SHR, WKYO rat strains.
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